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By Alex Kreisman, Media Center of Excellence, IRI, and Marc Guldimann, CEO, Adelaide

Marketers have an ever-growing selection of metrics to measure digital media at their disposal. But not all of them use the rigor of evidence-based methodologies to prove effectiveness.

Take viewability, for instance. According to the standards of the Interactive Advertising Bureau (IAB), a digital ad is considered viewable if 50% of the ad’s pixels are visible in the browser window for one second. It’s clearly valuable for marketers to know whether the audiences they are trying to reach can see their digital ads. But viewability, like other KPIs used in isolation, has limitations. And it’s a metric that can lead marketers astray when misapplied.

Marketers who use viewability to chase the lowest possible cost per thousand impressions (CPM) can end up wasting money on tiny ads on big screens that, in practice, rarely capture attention. To give brands a more transparent measure of ad quality, IRI has started working with Adelaide, which has devised a way to move beyond viewability and take media quality measurement to the next level using its metric, AU.

AU is an omnichannel media quality score proven to predict the likelihood and quality of attention and the probability of subsequent outcomes. Signals used to calculate AU are captured through Javascript, web scanning, eye-tracking panels and third-party data.

Advertisers who optimize their campaigns with AU can see up to an 80% improvement in ad impact.

IRI Lift™ can incorporate Adelaide AU into the final sales measurement deliverable. This functionality gives marketers the ability to test and learn by comparing the sales lift achieved from AU-optimized media and other optimization tactics, like viewability. IRI uses a forensic test and control method to ensure tightness of fit to accurately measure incrementality against various test groups.

Danone, a mutual client of IRI and Adelaide, has started using this approach as it is searching for media metrics that are predictive of KPIs across the entire marketing funnel. Initial results were successful, finding a correlation between AU-optimized media and sales lift. This combination of Adelaide AU Measurement with IRI Sales Lift Measurement is helping to provide Danone with the tools it needs to maximize every media dollar and improve sales results.

With consumer attention at a premium in our distracted world, marketers need proven tools that maximize their campaign results. This is another one that can get them closer to success.

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The National Basketball Association is scoring higher tune-in for live games by optimizing its media planning using attention, including on connected TV.The National Basketball Association is scoring higher tune-in for live games by optimizing its media planning using attention, including on connected TV.

The league has been on the hunt for a more effective real-time optimization metric tied to larger business goals, like brand lift and tune-in, said Larisa Johnson, VP of paid and CRM media at the NBA.

That need became imperative coming out of 2020. The NBA knew it possessed a strong brand that was highly relevant culturally, with players pushing for social justice reforms after the murder of George Floyd and following the successful completion of an entire playoff season in a bubble with only minimal setbacks.

But ratings were down. So the NBA was looking to shake things up in its channel mix and choose placements that were more predictive of positive outcomes.

“With business metrics only being available post-flight, we were previously operating in the dark while the campaign was live,” Johnson said.

With help from its media buying partner, IPG-owned Mediahub, the NBA started experimenting with a new CTV product from Adelaide, a startup that’s developing an attention-based ad currency it calls the “attention unit” (AU).

As opposed to viewability, which measures the opportunity for an ad to be seen, AU aims to help advertisers predict the opportunity to grab attention tied to likely outcomes across channels.

“Advertisers need an omnichannel metric that’s more broadly applicable than viewability,” said Marc Guldimann, Adelaide’s CEO and founder. “Viewability only makes sense in scrolling environments.”

Media placements are given quality scores that rate how likely they are to capture attention. If you capture attention, positive business outcomes follow. Adelaide uses a mix of different machine learning algorithms depending on the channel to analyze whichever signals are the likeliest predictors of quality and attention.

On the web, those signals usually include the position of a media placement, the duration of exposure and the amount of clutter on a page. But it’s a completely different story on CTV, where attention-grabbing signals include the ad pod, the genre and the time of day when an ad runs.

When Mediahub started looking at CTV media quality through the AU lens as part of the planning process for the NBA last year, it noticed a massive spread between what Adelaide characterized as low-attention versus high-attention placements.

“That gave us a clear, tactical way to optimize our plan by moving money from low to high attention media,” said Ed McElvain, EVP for digital platforms and data-driven media at Mediahub.

By focusing its media budget on high-attention placements across both CTV and digital, the NBA saw a 36% higher tune-in rate for live games compared to when it bought against placements with a lower AU score.

The NBA now uses AU as its main optimization metric, Johnson said, which “helped justify that the cost of certain premium placements really are worth the price tag.”

Adelaide and Mediahub are in the process of working together to co-develop media buying and planning technology that bakes in attention-based media quality metrics.

Although startups like Adelaide have been trying to make attention metrics happen for years, it’s been slow going. Ad buyers are accustomed to their familiar proxy metrics, and they’ve been loath to change, even though most know they could be getting more out of their media.

But the end of third-party cookies and the general move toward more privacy-protective technologies is making advertisers more amenable to trying a different approach, Guldimann said.

“They’ve always known that not all impressions are the same, but they’ve been able to rely on attribution systems to see where they’re getting value,” he said. “As that becomes less tenable, there’s more of a desire to understand the quality of the media they’re buying.”

The fact is, attribution is turning into “swiss cheese,” McElvain said.

“We may or may not be able to know the action someone took based on the device or the preferences of an individual, but we can use attention to influence our buying without having to rely on a workaround,” he said. “We’re seeing a lot more clients open to having that conversation this year than last year.”

By Nate Doughty – Reporter

December 09, 2021, 11:28am EST

Strip District-based Niche, a company that provides users with a platform of rankings on schools, colleges and places to live, announced two new executive team appointments following a year-long hiring spree that has increased employee count by more than half.

Andra Smith joins the company as its first general counsel and corporate secretary. With more than 15 years of experience running legal departments, Smith has worked at companies like KAYAK, OpenTable and TicketNetwork. As general counsel and corporate secretary, Smith will be tasked with crafting privacy and compliance initiatives in new markets, overseeing the company’s corporate governance and internal processes and developing a series of best practices aimed at continuing to scale the quickly growing company. Smith will also serve as lead counsel for all of Niche’s commercial and financial transactions and will serve as secretary on the company’s board.

Morry Mitrani will serve as Niche’s first vice president of growth and lifecycle, a role he’ll take on following previous work at online dating platform Bumble Inc. (NASDAQ: BMBL). Mitrani joined Bumble during the company’s early stage period and led its global user acquisition teams through an acquisition by Blackstone Inc. (NYSE: BX) and Bumble’s eventual IPO. He’s logged more than 10 years of experience in digital marketing, working at other companies like IT networking platform Spiceworks and advertising agency GSD&M, both based in Austin, Texas. At Niche, Mitrani will oversee the growth, lifecycle and brand marketing teams that support the company’s scaling efforts, implementing new strategies that aim to retain and grow the user base.

“I’m incredibly excited to have Andra and Morry onboard at such a pivotal moment for the company,” Luke Skurman, CEO and co-founder of Niche, said in an email statement. “Andra brings invaluable legal and corporate expertise that will allow us to scale effectively and adopt best practices in contracts, compliance, user privacy and more. Morry’s previous successes using newer platforms to engage a similar audience will help expand our reach and build our brand in the next phase of our business. I’m very much looking forward to working closely with each of them.”

The two new appointments come after a year-long effort of significant employee onboarding for the Pittsburgh company.

At the start of 2021, Niche had 156 full-time employees. Now, it’s at 241 full-time workers across 27 states, a 54% increase in headcount from less than 12 months ago. It’s also now up 20% in workers since September, which is when the company first surpassed employing more than 200 workers.

“The headline with Niche right now is that we have happy users, we have happy clients, we’re a successful Pittsburgh company that’s scaling and growing right now and really hitting the stride right now,” Skurman said in September. “And yes, we are hiring aggressively right now. We anticipate hiring another 100 people over the next year in all facets of the business — engineering, product, design, sales, marketing, all across the board — it’s a really exciting time in the company right now.”

Founded in 2002 and initially named CollegeProwler by then-Carnegie Mellon University Tepper School of Business students Skurman and Joey Rahimi, the company has since evolved from its original form of publishing print guidebooks on U.S. colleges to one that posts online rankings of K-12 schools, colleges, cities, neighborhoods and companies throughout the nation. In April 2020, it raised $35 million in Series C funding led by Radian Capital and with participation from Salesforce Ventures, as well as the company’s existing investors; Allen & Co. LLC and Tim Armstrong.

https://www.bizjournals.com/pittsburgh/inno/stories/news/2021/12/09/niche-appoints-two-executives-amid-hiring-spree.html

 

By Jordyn Hronec  –  Digital Producer, Pittsburgh Business Times

Sep 22, 2021, 12:28pm EDT

Peptilogics, a biotech company based on the South Side, will be presenting data it collected from the first-in-human Phase 1 of its lead investigational therapy for the treatment of prosthetic joint infection (PJI). The presentation will take place at the IDWeek 2021 conference.

The company, which engineers peptide therapeutics in order to change the treatment landscape for patients with life-threatening diseases, has optimized the therapy, known as PLG0206, for both safety and broad-spectrum activity against biofilms, which are produced by bacteria that harbor and protect bacteria from most antibiotics.

The PLG0206 therapy has been granted FDA Orphan Drug Designation and Qualified Infectious Disease Product Designation for the treatment of PJI. It targets and disrupts bacterial membranes, thus leading to the rapid killing of bacterial cells. It was announced in February of 2020 that Peptilogics would receive funding for clinical studies of the treatment from CARB-X, or Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator, a global nonprofit partnership based at Boston University School of Law.

Following joint replacement procedures, 1-2% of patients will develop a PJI. These infections are serious and life-threatening, and often require major surgeries to resolve, which carry a 60% failure rate. The mortality rate for surgeries intended to resolve PJIs over a five year period is 25%.

At the IDWeek 2021 conference, Peptilogics will present data from three accepted abstracts:

  • “A Phase 1 safety and tolerability of single ascending doses of a novel engineered Cationic Peptide, PLG0206, in healthy subjects,” which includes clinical safety data;
  • “Knee explant analysis (KnEA) using PLG0206 in periprosthetic joint infection (KnEA Study),” which includes results from a PJI patient explant study;
  • “In vitro activity of PLG0206 against isolates commonly found in periprosthetic joint infections,” which includes information on in vitro activity against bacteria commonly found in PJIs.

IDWeek is the joint annual meeting of several organizations: the Infectious Diseases Society of America (IDSA), Society for Healthcare Epidemiology of America (SHEA), the HIV Medicine Association (HIVMA), the Pediatric Infectious Diseases Society (PIDS), and the Society of Infectious Diseases Pharmacists (SIDP). IDWeek 2021 is a virtual conference taking place from Sept. 29 through Oct. 3.

https://www.bizjournals.com/pittsburgh/news/2021/09/22/peptilogics-to-present-new-data-at-idweek-2021.html?utm_source=st&utm_medium=en&utm_campaign=me&utm_content=pi&ana=e_pi_me&j=25120413&senddate=2021-09-23

SUNNYVALE, CA and PITTSBURGH, PA – August 18, 2021 – Cerebras Systems, the pioneer in high performance artificial intelligence (AI) compute, and Peptilogics, a biotechnology platform company and an emerging leader in leveraging computation to design novel therapeutics, today announced a collaboration to accelerate the development cycle of peptide therapeutics through AI.

Leveraging the revolutionary Cerebras CS-2 system – powered by the world’s fastest AI processor – Peptilogics will be able to push the boundaries of innovation in drug design and novel peptide therapeutics. This cutting-edge exploration of innovation is a scientific game changer with the potential to meaningfully reduce the time from bench to bedside.

“Our mission at Peptilogics is to radically alter drug development and realize the full potential of peptides as therapeutics,” said Nick Nystrom, PhD, SVP and Head of Computation and Data, Peptilogics. “By partnering with Cerebras, we will be able to accelerate our research by orders of magnitude for important areas such as membrane proteins, including G protein coupled receptors (GPCRs). Traditional drug discovery operates on the time scale of one new drug in ten years. We aim to flip that to ten new leads in one year.”

Peptides are sequences of amino acids, essentially small proteins, that play critical roles in how our bodies operate. They offer relatively unexplored opportunities for therapeutics, conferring potential advantages over other types of drugs. The “design space,” or number of possible peptide structures, is vastly larger than could be explored through traditional drug discovery. AI – specifically deep learning – is well-suited to identify ideal peptide structures as drug candidates.

Through this collaboration, Cerebras and Peptilogics scientists will use the CS-2 system to develop and run advanced models to identify novel peptide therapeutics that meet specific biological activity and biophysical criteria. By accelerating the slowest step of the research cycle and training deep learning models on big data, Peptilogics with Cerebras will be positioned to deliver better therapeutics sooner. Peptilogics joins other life science leaders, including GSK and AstraZeneca, in leveraging Cerebras’ industry-leading AI technology to advance drug discovery.

“Peptilogics is operating at the forefront of AI-enabled drug design. With Cerebras, they are part of a select group of partners that share similar interests in pushing the boundaries of scientific research and AI computing to radically accelerate innovation for better healthcare outcomes,” said Andy Hock, VP of Product at Cerebras. “Cerebras Systems makes world-leading AI compute accessible and easy to use so that our partners at Peptilogics can test more ideas quickly, reduce the cost of curiosity, and achieve their mission of discovering peptide therapeutics in record time.”

For more information, please visit https://cerebras.net/industries/health-and-pharma/.

About Cerebras Systems
Cerebras Systems is a team of pioneering computer architects, computer scientists, deep learning researchers, and engineers of all types. We have come together to build a new class of computer to accelerate artificial intelligence work by three orders of magnitude beyond the current state of the art. The CS-2 is the fastest AI computer in existence. It contains a collection of industry firsts, including the Cerebras Wafer Scale Engine (WSE-2). The WSE-2 is the largest chip ever built. It contains 2.6 trillion transistors and covers more than 46,225 square millimeters of silicon. By comparison, the largest graphics processor on the market has 54 billion transistors and covers 815 square millimeters. In artificial intelligence work, large chips process information more quickly producing answers in less time. As a result, neural networks that in the past took months to train, can now train in minutes on the Cerebras CS-2 powered by the WSE-2.

About Peptilogics
Peptilogics is a clinical-stage biotechnology platform company that designs and develops novel peptide therapeutics. The company is supported by investors including Presight Capital, Founders Fund, and Peter Thiel, who are known for their investments in companies such as AbCellera (NASDAQ: ABCL), Compass Pathways (NASDAQ: CMPS), SpaceX, and Synthego. Through its computational platform, Peptilogics is advancing drug discovery to uncover new, previously unexplored chemical design space, while ensuring biological viability and scalable manufacturing. Peptilogics’ anti-infectives pipeline includes a novel clinical stage anti-infective, PLG0206, that has been granted FDA Orphan Drug Designation and Qualified Infectious Disease Product Designation for its initial focus on the treatment of prosthetic joint infections, an urgent unmet medical need. More information on Peptilogics can be found at www.peptilogics.com as well as on Twitter and LinkedIn.

Cerebras Media Contact:
Kim Ziesemer
Email: pr@zmcommunications.com

Peptilogics Contact:
Jodie Gillon
SVP Corporate Affairs & Patient Advocacy
Email: jodie.gillon@peptilogics.com

Hemolung® RAS Used to Treat More than 75 COVID-19 Patients(Photo: ALung Technologies, Inc.)

PITTSBURGH–(BUSINESS WIRE)–ALung Technologies, Inc., the leading provider of low-flow extracorporeal carbon dioxide removal (ECCO2R) technologies for treating patients with acute respiratory failure, announced that it has now treated more than 75 COVID-19 patients, and that it is experiencing increasing demand for the Hemolung® Respiratory Assist System (RAS) as a result of the current pandemic. The Food and Drug Administration (FDA) granted the Company Emergency Use Authorization (EUA) designation to the Hemolung RAS for the treatment of COVID-19 patients in the second quarter of 2020. The Hemolung is the only ECCO2R device currently granted an EUA for the treatment of COVID-19.

“The Hemolung RAS has enabled us to recover patients with COVID pneumonia during the pandemic. In select patients where there is a selective issue with hypercarbic respiratory acidosis while their oxygen requirements have normalized post-Veno-Venous ECMO cannulation, we have utilized Hemolung as a bridge in their recovery. We have noticed that these patients are able to wean off mechanical circulatory support in a gradual manner. Additionally, at a time when there was a shortage of ECMO circuits, our program has relied on utilizing this technology in stabilizing patients with severe hypercarbic respiratory acidosis while providing lung protective ventilation,” stated Dr. Bindu Akkanti, MD, Associate Professor of Medicine, Divisions of Critical Care, Pulmonary and Sleep Medicine, McGovern Medical School, and Director of Heart and Vascular Critical Care, Memorial Hermann – Texas Medical Center.

“The Hemolung RAS has given us a new tool during the current pandemic, to safely and easily treat our COVID-19 patients. We were able to rapidly introduce the Hemolung RAS to our staff and start treating patients under Emergency Use Authorization. As a smaller community hospital without an ECMO program, the ease of use of the Hemolung has played a large role in the successful deployment of ECCO2R for the treatment of COVID-19 at Palm Beach Gardens Medical Center,” stated Ribal Darwish, MD, Medical Director Critical Care Medicine, Palm Beach Gardens Medical Center.

“We are pleased to be able to assist in this fight against the COVID-19 viral disease by providing the use of the Hemolung RAS as a tool for physicians to be used in conjunction with IMV, by reducing or eliminating the potential of further lung damage caused by high ventilator driving pressures, often referred to as Ventilator Induced Lung Injury (VILI). We are treating COVID-19 patients in greater than 20 hospitals worldwide,” said Mr. Peter M. DeComo, Chairman and CEO of ALung Technologies.

In its EUA approval letter to ALung the FDA stated that it believes the Hemolung RAS has the potential to treat lung failure as an adjunct to noninvasive or invasive mechanical ventilation, to reduce hypercapnia and hypercapnic acidosis due to COVID-19, and/or to maintain normalized levels of partial pressure of carbon dioxide(PCO2) and pH in patients suffering from acute, reversible respiratory failure due to COVID-19 for whom ventilation of CO2 cannot be adequately, safely, or tolerably achieved and, in turn, may provide clinical benefit, and that there is no adequate, approved and available alternative to the emergency use of the Hemolung RAS to treat lung failure caused by COVID-19.

About ALung Technologies

ALung Technologies, Inc. is a privately held Pittsburgh-based developer and manufacturer of innovative lung assist devices. Founded in 1997 as a spin-out of the University of Pittsburgh, ALung has developed the Hemolung RAS as a dialysis-like alternative or supplement to mechanical ventilation. ALung is backed by Philips, UPMC Enterprises, Abiomed, The Accelerator Fund, Allos Ventures, Birchmere Ventures, Blue Tree Ventures, Eagle Ventures, Riverfront Ventures, West Capital Advisors, and other individual investors.

For more information about ALung and the Hemolung RAS, visit www.alung.com.

For more information on the VENT-AVOID trial, and a list of enrolling sites, please visit clinicaltrials.gov.

For more information on the use of the Hemolung RAS for COVID-19 patients, please visit https://www.alung.com/covid-19/covid-19-us/

*The Hemolung RAS has not been FDA cleared or approved.

*The Hemolung RAS has been authorized for the above emergency use by FDA under an EUA.

*This device is authorized only for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of the Hemolung RAS under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb- 3(b)(1), unless the authorization is terminated or revoked sooner.

This press release may contain forward-looking statements, which, if not based on historical facts, involve current assumptions and forecasts as well as risks and uncertainties. Our actual results may differ materially from the results or events stated in the forward-looking statements, including, but not limited to, certain events not within the Company’s control. Events that could cause results to differ include failure to meet ongoing developmental and manufacturing timelines, changing GMP requirements, the need for additional capital requirements, risks associated with regulatory approval processes, adverse changes to reimbursement for the Company’s products/services, and delays with respect to market acceptance of new products/services and technologies. Other risks may be detailed from time to time, but the Company does not attempt to revise or update its forward-looking statements even if future experience or changes make it evident that any projected events or results expressed or implied therein will not be realized.

KDKA:  https://pittsburgh.cbslocal.com/2020/12/09/pittsburgh-based-cytoagents-drug-trial-coronavirus-treatment/.

Pittsburgh Post-Gazette: New COVID-19 treatment shows encouraging early results, North Shore biotech company says

Pittsburgh Business Times: How CytoAgents’ plans for growth run far beyond Covid crisis

WTAE Pittsburgh: Pittsburgh-based company behind ‘promising’ new COVID-19 treatment

Fox 43 News: Pennsylvania biotechnology company testing new drug that could change the way COVID-19 patients are treated

WPXI Wolf Administration Highlights CytoAgents New Therapy Development  

New C360 CEO Howard Wright Sees Broadcast Tech Putting Fans on the Field of Play

The technology evangelist will focus on relationships and strategy in his new role

Howard Wright is not a new face in the industry — he was VP of global business development for Intel Sports and, prior to that, at Qualcomm — but he does have a new role: CEO, C360 Technologies, the Pittsburgh-based company whose technology has been used for such events as the Super Bowl, ESPN’s MNF, and major college football games. At both Qualcomm and Intel Sports, he honed his skills as a technology evangelist and also had a chance to develop relationships with some of the world’s top CTOs, league commissioners, and broadcasters.

C360’s Howard Wright: “We’re going up the stack and becoming an immersive-media–creation engine for the most valuable partners and teams and leagues in the world.”

“That takes a very special set of skills, and I am lucky to have learned them,” he says. “Some of those skills have been instilled in me by some of the greatest minds in telecommunications or mentors or friends to this day.”

Wright likes to refer to himself as a wannabe engineer going all the way back to his days at Stanford University, where he graduated with a bachelor’s degree in qualitative economics.

“I like to see how something goes from an idea on a whiteboard, into a patent pool, and then becomes something that permeates every part of our lives,” he says. “That fourth-dimension chess game has been what has kept me in high tech all these years.”

Evan Wimer, co-founder/CBO, C360, says that Wright’s skills will allow Wimer to focus on product development and other initiatives while Wright zeros in on relationships and strategy. He adds that Wright’s joining the company coincides with the closing of a round of financing with SeventySix Capital and that Wayne Kimmel, managing partner, SeventySix Capital, is now on the C360 board of directors.

“That gives us another weapon and insights at our disposal, which is tremendous and benefits our company,” Wimer adds.

He notes that innovation at C360 has always been about bringing a level of quality that fits into a production and, at the same time, brings a whole new set of opportunities to personalize the fan experience.

For C360, that innovation is a 10K camera system small enough to be mounted on a football yardage marker. Coupled with a wide-angle lens, it allows an operator to remotely pan, tilt, and zoom within the image, offering dynamic replays that can ensure a key moment isn’t missed.

That same system can also be tied into a live OTT or VR experience to allow the viewer to do their own pan, scan, and zoom.

“With betting,” Wimer points out, “the ability to select a particular player and track them throughout the whole game is where the future of sports is going. We can leverage the linear and OTT experience at the same time, and we continue to do things like add more digital zoom. That and color matching are two things we are [focusing on].”

Wright says that the evolution of consumer technologies coupled with broadcast technologies is creating the ability for fans to be on the field of play or follow players the way Wimer mentions.

“We want to create an option value for the broadcasters, for social, linear, and digital, and that is the part where Evan and I spend most of our time,” Wright says. “C360 isn’t just a pylon-cam company. It’s not a VR company. It’s not an AR company. The idea is that we’re going up the stack and becoming an immersive-media–creation engine for the most valuable partners and teams and leagues in the world. That’s the unapologetic goal.

“What we have at C360,” he continues, “is a very simple weapon to be utilized by the broadcasters and, ultimately, by OTT players. And what we’re trying to do is increase the efficiency, increase the efficacy, increase the horsepower of our solution so that it can service this industry and the other industries that we service.”

To help get to those goals, Wright says, he follows the Servant Leadership principles.

“You need to take and close action items as much as you need to give them,” he says. “You need to be an active listener and not a dictator. And you need to be a trusted member of the team that is working alongside the rest of the team, regardless of status, regardless of equity, regardless of title. The goal is to harness and galvanize the collective IQ of our staff and investment community. That’s going to propel us as forward.”

Adds Wimer, “Howard is the kind of person that we really needed and have looked for to lead the company. There couldn’t be a better person paired for the next growth cycle of the company.”

Local Biotech Firm Develops Drug For Respiratory Distress In COVID-19 Patients

  10 HOURS AGO

Pittsburgh-based biotech company CytoAgents is launching into phase one of clinical trials this month on a drug designed to treat people with COVID-19 who develop serious respiratory distress when their immune system overreacts to the virus.

According to CytoAgents CEO Teresa Whalen, severe illness in some patients is triggered by a cytokine storm which is an excessive immune response that attacks the body. She said the drug could be particularly helpful for someone hospitalized with COVID-19.

“Our drug will be used as soon as the patient enters the hospital to keep the patient from progressing to the ICU and avoiding the need for ventilators,” Whalen said.

The drug, GP 1681, is given orally and Whalen said that makes it more affordable than traditional immunotherapy treatments known as biologics which are often administered intravenously.

“Biologics are more than $10,000 for one course of therapy and we would likely be in the hundreds, possibly low one thousands, so there is a significant difference,” Whalen said.

In addition to COVID-19, Whalen said the drug is designed to combat cytokine storm in other infectious diseases like influenza.

“We are really excited by the potential of the science and the fact that we could be therapeutically helpful for not only this pandemic but many future pandemics,” Whalen said. She also noted her company is working with partners to conduct drug trials to treat people who have suffered intense respiratory failure and lung damage caused by vaping.

In July, CytoAgents announced it received an investment of $250,000 from the Richard King Mellon Foundation to support its first phase of clinical trials. The funding is part of the foundation’s $25 million Pandemic Solutions package to help local organizations respond to the coronavirus crisis.

CREDIT CYTOAGENTS

Other pandemic assistance from RK Mellon includes $2.5 million to help colleges and universities in western Pennsylvania cover additional expenses they will incur as they reopen for the fall semester.

Debut on NFL Kickoff Game – Thurs., Sept. 10, 8:20 p.m. ET on NBC – Marks First NFL Broadcast with Immersive Replays from Overhead

STAMFORD, Conn. – August 27, 2020 – NBC’s Sunday Night Football, primetime television’s #1 show for an unprecedented nine consecutive years, will present viewers with a unique overhead replay perspective this season with the innovative C360 camera, which is expected to yield looks at everything from the techniques of linemen along the line of scrimmage to plays along the sidelines.

Beginning with the NFL Kickoff Game on Thurs., Sept. 10 at 8:20 p.m. ET on NBC, and continuing throughout the NBC SNF season, the camera will provide for the first time on an NFL broadcast an immersive overhead replay experience.

The C360 camera will fly attached to the bottom of SkyCam to provide up-close and intimate replays of the game inside the tackle box, illuminating the talents of stars like Los Angeles Rams defensive tackle Aaron Donald and Dallas Cowboys guard Zach Martin in a way not previously seen on NFL telecasts. In addition, because the camera shoots in 8K and records in a 180-degree immersive field of view, production can go back in time to reframe a play to better provide definitive views from C360.

If there’s a question about a receiver catching a pass on the sideline, the technology can freeze the entire image, zoom in and focus on the player’s hands to confirm possession, before panning down to the player’s feet and zooming in to confirm both touched the ground before going out of bounds.

“We are excited to provide some of the most compelling overhead replays that football fans have ever seen, and look forward to working with C360 Technologies on this presentation,” said Fred Gaudelli, executive producer of NBC Sunday Night Football.

“We’re thrilled to be working with NBC Sports and to provide this novel immersive capability.  As a secondary camera on SkyCam, we anticipate capturing a fresh perspective of the game over the trenches,” said Evan Wimer, co-founder of C360 Technologies.

The C360 camera technology has previously been used in car on NASCAR on NBC broadcasts, and was nominated for a 2019 Sports Emmy for its use while embedded within line-to-gain pylons and first-down markers last season.

ABOUT C360 TECHNOLOGIES, INC.

C360® is personalizing the sports viewing experience. We’ve entertained millions of viewers worldwide while working with the largest sports broadcasters and Fortune 500 companies across the globe. Our platform integrates the smallest, most innovative cameras and patented software with v-commerce, sports betting and player/object tracking.  C360 is leading the personalized viewing revolution across every streaming channel, device and social media service allowing unlimited viewers to control their own fully immersive viewing experience.

– NBC SPORTS –

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